MARJOLINS ULCERS A CASE SERIES AND LITERATURE REVIEW

View at Google Scholar A. The patient refused the extensive surgery necessary to remove the infiltrating tumor, and the wound was closed with a latissimus dorsi flap. Right, large, loculated, peripheral enhancing collection is observed in the subcutaneous tissue of the auricular region, posterior and anterosuperior to the external auditory canal and extending to the mastoid air cells and middle ear cavity. One of our patients no. Biopsies were taken from the edges and centre of the lesion.

The most commonly involved areas of the head are the scalp [ 1 , 6 ] and face [ 1 , 10 ]; in one reported case, the nose was affected [ 12 ], and in another, the neck was affected [ 8 ]. Biopsy of the ulceration showed a high-grade pleomorphic sarcoma in the Marjolin’s ulcer. In the dermatology and oncology literature, the treatment recommended is wide resection including a safety margin several centimeters wide, with the width depending on the size of the tumor and the extent to which it is likely to evolve [Ames and Hickey [ 20 A mes FC, H ickey RC: Cancer, , 52, Many cases of acute transformation, ranging from weeks [ 18 , 20 ] to months [ 7 , 14 , 21 ], have been reported in the literature. Report of three cases.

Many cases of acute transformation, ranging from weeks [ 1820 ] to months [ 71421 ], have zeries reported in the literature. Marjolin’s ulcer is a malignant transformation of traumatized or chronically inflamed cutaneous tissue that occurs after burns.

Rev Chir Orthop,79, Treatment with Mohs micrographic surgery vs amputation.

Biopsies were taken from the edges and centre of the lesion. The histopathology results were consistent with cholesteatoma Figure 3. Squamous-cell carcinomachronic osteomyelitisMarjolin’s ulcer.

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marjolins ulcers a case series and literature review

In the majority of cases, this is squamous-cell carcinoma. Biopsy material should be obtained whenever there is a modification leading to the development of a fistula or the formation of scar tissue over a focus literautre chronic osteitis.

Marjolin’s ulcer complicating a pressure ulcer: Case report and literature review

Malignancy in chronic osteomyelitis luterature. However, it has been reported in others areas in the head and neck. J Burn Care Rehabil,12, Click here to see the Library ] series, that this name was also applied to neoplastic transformations with onset on sites of chronic bone infection.

View at Google Scholar M. Squamous cell carcinoma is the most prevalent malignancy identified in Marjolin’s ulcers and was confirmed in all patients in this study. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The toxins theory, which proposes that the chronic inflammatory processes that lead to tissue damage produce toxins that may be carcinogenic, was proposed by Treves and Pack [ 11 ].

View at Google Scholar B. The patient had no medical illness and was negative for human immunodeficiency virus. This high mean age is explained by the long period of progression necessary for the development of degeneration of chronic wounds and fistulae. Ann Oncol,3 suppl. Wide local excision and subsequent skin grafting appear to be the ulcrrs of care for most authors [ 8 ].

Marjolin’s Ulcers: A Case Series and Literature Review.

Chir Organi Mov,84, One of our patients no. Report of three cases.

marjolins ulcers a case series and literature review

Amputation remains a very important option in treating Marjolin ulcers, lesions that are rarely discovered at the initial stage with little progression. Outline Masquer le plan.

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Orthop Rev,20, In the dermatology and oncology literature, the treatment recommended is wide resection including a safety margin several centimeters wide, with the width depending on the size of the tumor and the extent to which it is likely to evolve [Ames and Hickey [ 20 A mes FC, H ickey RC: Squamous cell carcinoma arising in chronic osteomyelitis. One must take into account the function that would be restored if the limb were saved after conservative surgery, with sometimes long aftereffects, and weigh this with the rapid return to function that a esries on a stump in good condition after radical surgery would give.

These cases underscore the aggressive course and poor prognosis associated with Marjolin’s ulcers and the importance casse recognizing the potential for malignant transformation of a chronic wound. J Dermatol Surg Oncol,12, Personal information regarding our website’s visitors, including their identity, is confidential.

Right, large, loculated, peripheral enhancing collection is observed in the subcutaneous tissue of the auricular region, posterior and anterosuperior to the external auditory canal and extending to the mastoid air cells and middle ear cavity. The male-to-female ratio increases with increasing patient age over 50 years [ 101116 ].

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